发明名称 APPARATUS AND METHOD FOR DELIVERING A BIOLOGICALLY ACTIVE COMPOUND INTO A BIOLOGICAL ENVIRONMENT
摘要 System for delivery of a biologically active substance into an environment. First and second chambers are separated by a moveable partition. The first chamber includes a polymer gel network which undergoes a volume change in response to an environmental condition such as pH. The first compartment includes a screen or membrane for confining the polymer gel network while allowing communication with fluid in an environment. The second compartment contains a biologically active compound or drug which is delivered to the environment through an orifice in the second compartment. Upon the occurrence of the triggering environmental condition, the polymer gel network undergoes a volume change which moves the moveable partition expelling the drug through the orifice. Drug delivery is initiated and continues only when the appropriate environmental condition or trigger is met.
申请公布号 WO9640082(A2) 申请公布日期 1996.12.19
申请号 WO1996US09416 申请日期 1996.06.05
申请人 GEL SCIENCES, INC. 发明人 RON, EYAL, S.;SCHILLER, MATTHEW, E.;ROOS, ERIC
分类号 A61K8/02;A61K8/04;A61K8/73;A61K9/00;A61K9/20;A61K9/22;A61K38/47;A61K47/38;A61L15/60;A61L26/00;A61L27/52;A61L27/54;A61L29/14;A61L31/14;A61Q13/00;A61Q19/00;C08B15/00;C08B31/00;C12N5/00 主分类号 A61K8/02
代理机构 代理人
主权项
地址