| 发明名称 |
TREATMENT OF INSULIN RESISTANCE |
| 摘要 |
Methods and compositions are provided for the treatment of insulin-resistance through the inhibition of protein kinase C-mediated phosphorylation of the amino acid residue Ser1270 of the insulin receptor. Methods for testing candidate compounds suitable for inhibition of serine-phosphorylation by protein kinase C are also provided.
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| 申请公布号 |
CA2223891(A1) |
申请公布日期 |
1996.12.19 |
| 申请号 |
CA19962223891 |
申请日期 |
1996.06.07 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
OLEFSKY, JERROLD M.;PILLAY, TAHIR S. |
| 分类号 |
C12N15/09;A61K38/00;A61K45/00;A61K48/00;A61P3/10;A61P43/00;C07K7/06;C07K14/72;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/12;C12N9/99;C12Q1/48;C12Q1/68;(IPC1-7):C12N15/17;A61K38/08;A61K38/28;A61K31/70 |
主分类号 |
C12N15/09 |
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