发明名称 CALCIUM CHANNEL ANTAGONISTS
摘要 A method for antagonizing or blocking calcium channels in vascular tissue, comprising administering to an animal in need thereof a pharmaceuticallyeffective amount of a compound having formula (I) wherein R1 and R3 are independently hydrogen, C1-C4 alkyl, -CO-(C1-C6 alkyl), or -CH2Ar, -CO-Ar, wherein Ar is phenyl or substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically-acceptable salt thereof.
申请公布号 CA2223711(A1) 申请公布日期 1996.12.19
申请号 CA19962223711 申请日期 1996.06.04
申请人 ELI LILLY AND COMPANY 发明人 COHEN, MARLENE LOIS
分类号 C07D333/56;A61K31/38;A61K31/381;A61K31/40;A61K31/4025;A61K31/445;A61K31/453;A61P1/00;A61P9/00;A61P9/12;A61P13/02;A61P15/00;(IPC1-7):A61K31/445;A61K31/55 主分类号 C07D333/56
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