| 摘要 |
<p>This invention features a method for triggering release of a drug from a hydrogel polymer (55) to tissue at a desired location of the body using a catheter. A portion of the catheter (51) is coated on its outer surface with a polymer (55) having the capacity to incorporate a predetermined substantial amount of drug which is immobilized in the polymer until released by a triggering agent or condition that is different from physiological conditions. Upon contact with a triggering agent or condition, the polymer reacts, e.g., swells or contracts such that the drug is delivered to the desired body tissue. A balloon catheter (51) is shown in which the hydrogel (55) is carried on the exterior surface of the balloon (54).</p> |
