摘要 |
Pharmaceutical compositions containing mono-, di-, and triphosphate esters of antiproliferative nucleoside analogues, DNA chain-terminating dideoxynucleoside analogues and other nucleoside analogues for the topical treatment of hyperproliferative diseases of the skin, including psoriasis. The useful phosphate esters of the nucleoside analogues include phosphoramidates and phosphothiorates, as well as polyphosphates having C and S bridging atoms.
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