| 摘要 |
PURPOSE: To obtain a cross-linked polysaccharide nonproblematic in poor strengths and early decomposability and capable of being actually used as a medical material by mixing an organic compound containing at least two aldehyde groups with an aqueous uncross-linked polysaccharide solution and drying the obtained mixture to form a sheety solid. CONSTITUTION: An organic compound having at least two aldehyde groups (e.g. glutaraldehyde) is mixed with an aqueous solution of an uncross-linked polysaccharide (e.g. hyaluronic acid), and the obtained mixture is dried to form a sheety solid. The thus obtained solid is one comprising a polysaccharide cross-linked through a hemiacetal or acetal bond formed by the organic compound having at least two aldehyde groups. According to the above process, a cross-linked polysaccharide nonproblematic in conventional poor strengths and early decomposability and capale of being satisfactorily and actually used as e.g. an adhesion inhibitor, a substrate for nervous regeneration, an artificial skin or a wound covering material. |
