| 摘要 |
PURPOSE: To obtain the subject liquid developing no deterioration of its appearance such as precipitation, getting turbid or suspended matter formation even after preserved over a long period, by formulating a licorice extract (licorice: Glycyrrhiza glabra) with specific stabilizer(s). CONSTITUTION: This liquid is obtained by formulating (A) a licorice extract with (B) polyvinylpyrrolidone and/or (B) polyoxyethylene and/or polyoxypropylene glycol. The amounts of the ingredients A, B and C to be formulated are pref. 0.01-5wt.%, 0.02-2wt.% and 0.02-1wt.%, in terms of the amount of the stock crude drug, respectively. Specifically, this liquid is obtained by the following process: the ingredient A is dissolved in water, and the resultant solution is formulated with the ingredient(s) B and/or C followed by, according as necessary, pH adjustment. Besides, this liquid can be formulated with extract(s) of crude drug(s) such as carrot, antitussive/expectorant, vitamin(s), alcohol(s), surfactant, sweetener, etc. This liquid clan be made, normally through heat sterilization, into an orally administrable liquid for internal use. |
