| 摘要 |
<p>Methods and composition are disclosed for producing air-activated, i.e., oxygen activated, disinfectant-sterilent solutions. Solutions containing a haloperoxidase (i.e., a halide: hydrogen peroxide oxidoreductase, such as myeloperoxidase, eosinophil peroxidase or lactoperoxidase) plus a halide or combination of halides (i.e., chloride, bromide and/or iodide), an oxidase (i.e., a substrate: oxygen oxidoreductase) capable of generating hydrogen peroxide, and a substrate specific for that oxidase, are separately prepared under aerobic conditions, but all of the component solutions are made anaerobic prior to final combination and mixing. The anaerobic formulations are dispensed into containers capable of maintaining the anaerobic condition (e.g., pressurized canisters). Dispensing the solution at the time of use exposes the formulation to air (i.e., oxygen) which activates its disinfectant-sterilent properties.</p> |
