Cloning and expression of toxoplasma antigens and use of recombinant antigens

摘要

PCT No. PCT/AU91/00347 Sec. 371 Date Apr. 12, 1993 Sec. 102(e) Date Apr. 12, 1993 PCT Filed Aug. 9, 1991 PCT Pub. No. WO92/02624 PCT Pub. Date Feb. 20, 1992A synthetic or recombinant polypeptide displaying the antigenicity of all or an antigenic fragment of the H4 or H11 polypeptides of Toxoplasma gondii, and recombinant DNA molecules, vectors and host cells for the expression thereof. Use of the polypeptide in vaccine compositions and in diagnostic immunoassays is also disclosed.