发明名称 Cytostatic or cytotoxic combination of active substances for use in therapeutic procedures
摘要 According to this invention the combination of active substances for use in therapeutic procedures consists of at least one cytostatic compound, e.g. vincristine, methotrexate, cisplatin as the first agent and at least one histone and/or one active histone fragment with cytostatic or cytotoxic activity as the second agent. Both active agents act synergistically at the site of the pathogenic process.
申请公布号 US5578571(A) 申请公布日期 1996.11.26
申请号 US19940310378 申请日期 1994.09.22
申请人 SYMBIOTEC GESELLSCHAFT ZUR FORSCHUNG UND ENTWICKLUNG AUF DEM GEBIET DER BIOTECHNOLOGIE MBH 发明人 ZEPPEZAUER, MICHAEL;LEINENBACH, HANS P.
分类号 A61K31/475;A61K31/505;A61K33/24;A61K38/00;A61K38/17;A61K45/06;A61P35/00;A61P43/00;(IPC1-7):A61K38/00;A01N37/18;C07K5/00;C07K7/00 主分类号 A61K31/475
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