| 发明名称 |
ANTITUMOR MEDICINAL CONJUGATES CLEAVAGED BY LYSOSOMAL ENZYMES |
| 摘要 |
FIELD: pharmacy. SUBSTANCE: invention relates to conjugates drug-ligand where drug is bound with ligand through the protein peptide linker and connecter and also to process of preparing indicated conjugates, method of inhibition of undesirable cell growth, pharmaceutical compositions and intermediate products for their. EFFECT: enhanced quality of conjugates. |
| 申请公布号 |
RU94016384(A) |
申请公布日期 |
1996.11.10 |
| 申请号 |
RU19940016384 |
申请日期 |
1994.05.13 |
| 申请人 |
BRISTOL'-MEJERZ SKVIBB KOMPANI |
发明人 |
RAJMOND ARMAND FAJRSTOUN;DZHIN MAJKL DUBOVCHIK |
| 分类号 |
A61K9/00;A61K39/385;A61K31/19;A61K38/00;A61K39/395;A61K47/48;A61P35/00;C07K5/02;C07K5/06;C07K5/065;C07K5/087;C07K14/42;C07K14/485;C07K14/495;C07K14/52;C07K14/54;C07K14/55;C07K14/575;C07K14/595;C07K14/62;C07K14/65;C07K16/00;C07K19/00;C12N9/50;G01N33/53 |
主分类号 |
A61K9/00 |
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