发明名称 |
HUMAN LEUKOCYTE 12-LIPOXYGENASE AND ITS ROLE IN THE PATHOGENESIS OF DISEASE STATES |
摘要 |
Evidence for the presence of a human leukocyte type of 12-LO enzyme and its role in the pathogenesis of several major disease states or processes, including atherosclerosis, breast cancer, autoimmune and inflammatory disease, diabetic vascular and kidney disease and insulin resistance is described. Mediation, including the blockage of the human leukocyte 12-LO expression or enzyme activation, provides novel treatment to prevent or ameliorate these disease states.
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申请公布号 |
WO9634943(A1) |
申请公布日期 |
1996.11.07 |
申请号 |
WO1996US06328 |
申请日期 |
1996.05.03 |
申请人 |
CITY OF HOPE;NADLER, JERRY, L.;NATARAJAN, RAMA |
发明人 |
NADLER, JERRY, L.;NATARAJAN, RAMA |
分类号 |
G01N33/573;A61K31/00;A61K31/045;A61K31/05;A61K31/155;A61K31/195;A61K31/20;A61K31/201;A61K31/202;A61K31/35;A61K31/352;A61K31/44;A61K31/4439;A61K31/575;A61K33/06;A61K38/00;A61K38/08;A61K38/18;A61K38/20;A61K38/46;A61K45/00;A61K48/00;A61P3/00;A61P3/10;A61P9/00;A61P9/10;A61P29/00;A61P35/00;A61P35/04;A61P37/00;C12N9/02;C12N9/99;C12Q1/26;G01N33/68;(IPC1-7):C12N9/02;A61K33/10 |
主分类号 |
G01N33/573 |
代理机构 |
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代理人 |
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地址 |
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