(2'-5') oligoadenylate analogues useful as inhibitors of host-v5.-graft response

摘要

PCT No. PCT/US91/05734 Sec. 371 Date Aug. 29, 1994 Sec. 102(e) Date Aug. 29, 1994 PCT Filed Aug. 12, 1991 PCT Pub. No. WO93/03733 PCT Pub. Date Mar. 4, 1993The invention deals with the production of analogues of adenylyl (2'-5')adenylyl (2'-5')-9-(2,3-anhydro- beta -D-ribofuranosyl) adenine disodium salt by the phosphotriester method. The pharmaceutical composition prepared according to this invention inhibits the host-vs.-graft response.