A fused polypeptide composed of a polypeptide having the G-CSF activity with another polypeptide having the TPO activity; a DNA encoding this fused polypeptide; a fused polypeptide wherein a polypeptide having the G-CSF activity has been fused with another polypeptide having the TPO activity via a spacer peptide; a DNA encoding this fused polypeptide; a polypeptide wherein the above-mentioned fused polypeptide composed of the polypeptide having the GCSF activity with the polypeptide having the TPO activity has been further chemically modified with a polyalkylene glycol derivative; and a remedy for anemia containing such a fused polypeptide as the active ingredient.
