| 摘要 |
PURPOSE: To obtain a dermal preparation for external use containing hydroxycarboxylic acids, excellent in moisture retaining action, capable of giving moist to a skin, preventing the skin from becoming rough and improving transparent feeling and darkness of the skin. CONSTITUTION: This dermal preparation for external use contains compounds or their salts expressed by formula I, II and III [R<1> to R<3> are each OH, an amino or an alkoxy of which 1-3 OH may be substituted; (l) is 7-11; (m) is 6-10; (n) is 5-9] as active ingredients. Their total content is 0.001-50wt.% based on the total composition in the case of an emulsion type dermal preparation for external use, and 0.1-50wt.% in the case of oily dermal preparation for external use. The blending molar ratio of the compounds of the formulae I, II and III is (60-95):(4-35):(1-10). By blending 3 kinds of hydroxycarboxylic acids or their salts, a dermal preparation for external use excellent in moisture retaining power into the corneal layer of the skin, the properties of manifesting and sustaining its effectiveness, and safety to the skin, is obtained.
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