Ikame edilen benzolsülfonilüre ve tiyoüre, bu maddelerin elde edilmesi ve eczanecilikle ilgili maddelerin bu bilesimler ve bu bilesimleri iceren iyilestirici maddelere dayanarak kullanilmasi ile ilgili usul.

摘要

Substd. benzene sulphonyl urea and thiourea cpds. of formula (I) and their salts are new. R1 = H, 1-7C alkyl or 3-7C cycloalkyl; R2 = H, 1-6C alkyl, 1-6C alkoxy, 1-6C mercaptoalkyl, 3-6C cycloalkyl, or 1-8C chain (in which 1-4C atoms are replaced by Het), F or Cl; R3, R4 = H, 1-12C alkyl, 3-10C cycloalkyl, 1-6C fluoroalkyl, 3-6C fluorocycloalkyl, or 1-10C chain in which 1-4C atoms are replaced by Het; or R3+R4 = (CH2)p, opt. with 1 or more CH2 replaced by heteroatoms; p = 2-8; Q, X = O or S; Y = (CR5R6)m; R5; R6 = H, Me or Et (opt. different in different CR5R6 gps.); Het = heteroatom such as O, N or S, m = 1-4.