DEVICE FOR THE STUDY OF ORGANOTYPIC CULTURES AND ITS USES INELECTROPHYSIOLOGY AND BIOCHEMISTRY

摘要

The present invention relates to the domain of electrophysiology and biochemistry and to the measuring devices in these domains. A more particular subject of the invention is a new device which enables tissular explants to be kept alive and the electrophysiological and biochemical activity of the tissue studied to be continuously collected and analyzed. This device is formed by two half-cards forming the upper part and the lower part respectively of the interface which are fitted together to form a card intended to be inserted in an electronic module specially designed for this purpose. This device is used for measuring the electrophysiological activity of excitable cells using a biocompatible multielectrode array and one or more microdialysis probes for biochemical or radioimmunoassays.