发明名称 Process for the production of combinatorial compound librari es
摘要 Described is a process for the production of a library from a plurality of different units consisting of a solid or semisolid carrier (bead), a synthetic ligand and a binary information structure (tag), by means of which the building blocks of the ligand are coded, and the use of that library for searching for novel classes of active ingredient and individual active ingredients. Also described are compounds found using that process. The process is characterized by the use of element atoms or ions as binary tags which are bound non covalently to the beads. Their unique combination which can be measured by e.g. mass spectrometry codes for the specific ligand.
申请公布号 AU5110096(A) 申请公布日期 1996.10.16
申请号 AU19960051100 申请日期 1996.03.18
申请人 CIBA-GEIGY AG 发明人 HANS RINK;DIRK VETTER;EDUARD FELDER;BERTOLD GERCKEN
分类号 A61K38/00;C07K1/04;C40B40/10;C40B70/00 主分类号 A61K38/00
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