发明名称 NOVEL HETEROCYCLIC COMPOUNDS
摘要 A compound of formula (I) in which Z is selected from (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), and (k). The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
申请公布号 WO9631498(A1) 申请公布日期 1996.10.10
申请号 WO1996DK00139 申请日期 1996.04.01
申请人 NOVO NORDISK A/S 发明人 DOERWALD, FLORENZIO, ZARAGOSSA;ANDERSEN, KNUD, ERIK;MADSEN, PETER;JOERGENSEN, TINE, KROGH;HOHLWEG, ROLF;ANDERSEN, HENRIK, SUNE;TREPPENDAHL, SVEND;OLSEN, UFFE, BANG;ZDENEK, POLIVKA;ALEXANDRA, SILHANKOVA;KAREL, SINDELAR
分类号 C07D223/28;A61K31/40;A61K31/4427;A61K31/445;A61K31/535;A61K31/538;A61K31/55;A61P3/08;A61P3/10;A61P25/00;A61P25/04;A61P29/00;A61P43/00;C07D207/16;C07D211/60;C07D211/62;C07D401/06;C07D403/06;C07D413/06;C07D453/02;(IPC1-7):C07D401/06 主分类号 C07D223/28
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