发明名称 |
Heterocyclic substituted piperazinone derivatives as tachykinin receptor antagonists |
摘要 |
The present invention relates to substituted piperazinone derivatives of formula (1) or stereoisomers, or pharmaceutically acceptable salts thereof and their use as tachykinin receptor antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions disclosed herein including: asthma, cough, and bronchitis. The present invention also relates to intermediates useful in the preparation of compounds of formula (1). |
申请公布号 |
AU4930696(A) |
申请公布日期 |
1996.10.02 |
申请号 |
AU19960049306 |
申请日期 |
1996.02.06 |
申请人 |
HOECHST MARION ROUSSEL, INC. |
发明人 |
TIMOTHY P. BURKHOLDER;ELIZABETH M KUDLACZ;TIEU-BINH LE |
分类号 |
A61K31/495;A61P11/00;A61P43/00;C07D209/04;C07D209/08;C07D209/20;C07D403/06;C07D403/14 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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