发明名称 |
Recombinant human cytomegalovirus containing foreign gene |
摘要 |
The present invention provides a virus comprising a DNA sequence essential for replication of a human cytomegalovirus and at least one foreign DNA sequence adapted for expression in a host. The foreign DNA sequence may encode a human immunodeficiency virus anti-sense mRNA sequence or an antigenic polypeptide, e.g., a malarial surface antigen. Also provided are therapeutic compositions and vaccines which comprise the novel viruses of the present invention.
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申请公布号 |
US5561063(A) |
申请公布日期 |
1996.10.01 |
申请号 |
US19930164220 |
申请日期 |
1993.12.09 |
申请人 |
SYNTRO CORPORATION |
发明人 |
HOCK, LISA J.;COCHRAN, MARK D.;MACDONALD, RICHARD D. |
分类号 |
A61K48/00;C07K14/16;C12N7/01;C12N7/08;C12N15/113;C12N15/869;(IPC1-7):C12N15/86;C12N15/00;C12N15/11 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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