发明名称 |
Stable hemoglobin reference solution |
摘要 |
A reference solution for calibrating and monitoring blood gas instrumentation that has a shelf line of two years or greater is disclosed. The solution is contained in a closed container having a gas or gas mixture that is inert to the reference solution and comprises an aqueous mixture containing a hemoglobin, a source of bicarbonate ions and an organic buffer. The solution optionally contains a methemoglobin reducing system, reference concentrations of selected electrolytes, a polyphosphate compound and antibiotics. The ampule is subsequently opened and the solution is equilibrated with a gas mixture having components which provide gasses in a physiological range to the solution. The solution is characterized by exhibiting properties similar to fresh blood subsequent to equilibration.
|
申请公布号 |
US5558985(A) |
申请公布日期 |
1996.09.24 |
申请号 |
US19940258505 |
申请日期 |
1994.06.10 |
申请人 |
BIONOSTICS INCORPORATED |
发明人 |
CHIANG, CHING;LIFFMAN, STANLEY M. |
分类号 |
G01N27/416;G01N33/96;(IPC1-7):C12Q1/00;C12Q1/60;C12Q1/56;G01N31/00 |
主分类号 |
G01N27/416 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|