发明名称 |
Process for preparing carbamoyl pyridinium compounds |
摘要 |
A process for synthesizing carbamoyl pyridinium compounds is described, in which the pyridine ring carries a sulfoalkyl group. The process comprises reacting a pyridine sulfonic acid with a carbamoyl chloride in the presence of a tert.-amine compound in a ketone solvent. The reactants are highly soluble in the ketone solvent, while, on the contrary, the carbamoyl pyridinium compounds and the tert.-ammonium halides formed by the reaction are not soluble in the ketone solvent and can be recovered from the reaction mixture. In a subsequent washing step with a selective solvent, for example in methanol in which carbamoyl pyridinium compounds are not soluble but tert.-ammonium halides are highly soluble, substantially pure carbamoyl pyridinium compounds can be obtained in high yields.
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申请公布号 |
US5559239(A) |
申请公布日期 |
1996.09.24 |
申请号 |
US19950459782 |
申请日期 |
1995.06.02 |
申请人 |
MINNESOTA MINING AND MANUFACTURING COMPANY |
发明人 |
VACCA, PAOLO;FREZZATI, MARCO |
分类号 |
C07D213/30;C07D213/34;C07D213/71;C07D401/06;C07D413/06;(IPC1-7):C07D213/81 |
主分类号 |
C07D213/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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