发明名称 |
ENZYME AMPLIFIED LANTHANIDE CHELATE LUMINESCENCE ASSAY |
摘要 |
<p>A method and compounds useful for this method are described for enzyme-amplified signal detection in analytical assays requiring extremely high detection sensitivity which uses a substrate capable of being transformed by an enzyme from a compound which does not form a luminescent lanthanide chelate into a product which forms a luminescent lanthanide chelate. The method in which a substrate not capable of forming a highly luminescent lanthanide chelate is enzymatically altered to produce a product which forms a highly luminescent lanthanide chelate and hence is particularly useful in time-resolved luminescence analysis as required in many different heterogeneous or homogeneous assay formats is described herein.</p> |
申请公布号 |
EP0544662(B1) |
申请公布日期 |
1996.09.18 |
申请号 |
EP19900916446 |
申请日期 |
1990.11.13 |
申请人 |
KRONEM SYSTEMS INC. |
发明人 |
EVANGELISTA, RAMON A.;TEMPLETON, EVA F. GUDGIN;POLLAK, ALFRED |
分类号 |
C12Q1/26;G01N33/533;G01N33/542;G01N33/58;(IPC1-7):G01N33/58;C07D471/04;C07C309/42;C12Q1/68;C07F9/12;C12Q1/25 |
主分类号 |
C12Q1/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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