| 摘要 |
PURPOSE:To provide a process for producing the subject ester useful as an intermediate raw material for the synthesis of functional materials, pharmaceuticals and agrochemicals in high yield. CONSTITUTION:This compound of formula II is produced by reacting 4bromoblphenyl with a phenol compound of formula I (R<1> to R<3> are each H, an alkyl, an alkoxy or an aryl; R<1> and R<2> are not sterically hindered groups at the same time) and carbon monoxide in the presence of an organic strong base (e.g. cyclic amidine or cyclic guanidine) using a palladium complex catalyst at 50-200 deg.C preferably 110-130 deg.C under carbon monoxide pressure of 1-50 bar, preferably 3-10 bar. The amounts of the phenol compound and the palladium complex are preferably 1.0-1.5mol and 0.002-0.008 mol based on 1mol of 4- bromobiphenyl, respectively. Even if the phenol compound has steric hindrance substituents on both 2- and 6-sites, the reaction is smoothly performed by using the phenol compound in the form of K salt or Na salt. |
