| 发明名称 |
REDUCTION OF INFARCT VOLUME USING CITICOLINE |
| 摘要 |
The invention is directed to a method of reducing the extent of infarction, particularly cerebral infarction subsequent to cerebral ischemia, by the administration of citicoline shortly after an ischemic episode and continuing daily treatment for up to about 30 days, preferably for at least about 6 weeks. The method is useful in the treatment of stroke and severe head trauma patients and maximizes the chances for a full or substantially full recovery of the patient. Combination treatment regimens are also disclosed along with compositions for use therewith.
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| 申请公布号 |
CA2213000(A1) |
申请公布日期 |
1996.09.12 |
| 申请号 |
CA19962213000 |
申请日期 |
1996.03.06 |
| 申请人 |
INTERNEURON PHARMACEUTICALS, INC. |
发明人 |
SANDAGE, BOBBY WINSTON;FISHER, MARC;LOCKE, KENNETH W. |
| 分类号 |
C07H19/10;A61K;A61K31/00;A61K31/505;A61K31/519;A61K31/529;A61K31/60;A61K31/612;A61K31/616;A61K31/66;A61K31/70;A61K31/7042;A61K31/7052;A61K31/706;A61K31/7064;A61K31/7068;A61K38/16;A61K38/48;A61K38/49;A61P7/06;A61P9/10;A61P25/00;A61P39/00;(IPC1-7):A61K31/70 |
主分类号 |
C07H19/10 |
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