发明名称 |
METHOD OF PURIFICATION OF RECOMBINANT VIRAL VECTORS CONTAINING A THERAPEUTIC GENE |
摘要 |
The invention provides a method of determining the number of intact viral particles in a sample, the method comprising: (a) chromatographing the sample containing the intact viral particles on an anion exchange resin; (b) monitoring the absorbance of the eluate from the chromatography of step (a) at a selected wavelength; and (c)determining the total number of intact viral particles in the sample by comparing the absorbance value obtained in step (b) to a standard curve which relates absorbance to number of viral particles.
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申请公布号 |
CA2522630(A1) |
申请公布日期 |
1996.09.12 |
申请号 |
CA19962522630 |
申请日期 |
1996.03.06 |
申请人 |
CANJI, INC. |
发明人 |
HUYGHE, BERNARD G.;SHABRAM, PAUL W.;LIU, XIAODONG;SHEPARD, H. MICHAEL |
分类号 |
G01N15/10;C12N7/02;C12N15/86;C12Q1/24;C12Q1/70;G01N21/31;G01N30/96 |
主分类号 |
G01N15/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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