PROCESS FOR PREPARING OPTICALLY ACTIVE AMINES

摘要

A new process is disclosed for preparing (R)-amines having the formula (I), in which R<1>, R<2> and n have the meanings given in the description. For that purpose, racemic N-acyl-amines having the formula (II), in which R<1>, R<2>, R<3> and n have the meanings given in the description, are reacted with lipases capable of splitting the (R)-enantiomers of N-acyl-amines having the formula (II), in the presence of water and optionally in the presence of an organic diluting agent at a pH value from 3,0 to 10,0 and at temperatures from 0 DEG C to 80 DEG C.