发明名称 2-BENZYL-3-ARYLBENZOTHIOPHENES
摘要 <p>The present invention provides derivatives of 2-phenylmethyl-3-¢4-(2-aminoethoxy)phenyl!-benzo¢b!thiophene. The present invention further provides pharmaceutical compositions containing these derivatives and the use of such compounds alone, or in combination with estrogen or progestin, for alleviating the symptoms of post-menopausal syndrome, particularly osteoporosis, cardiovascular related pathological conditions, and estrogen-dependent cancer. These compounds are also useful for inhibiting uterine fibroid disease and endometriosis in women and aortal smooth muscle cell proliferation, particularly restenosis, in humans.</p>
申请公布号 CA2214134(A1) 申请公布日期 1996.09.06
申请号 CA19962214134 申请日期 1996.02.27
申请人 ELI LILLY AND COMPANY 发明人 SALES, JAMES JOSEPH;CULLINAN, GEORGE JOSEPH
分类号 A61K31/38;A61K31/381;A61K31/40;A61K31/445;A61K31/535;A61P3/02;A61P3/06;A61P9/00;A61P13/02;A61P15/00;A61P43/00;C07D333/56;(IPC1-7):C07D333/58;C07D333/72;A61K31/55;C07F7/08 主分类号 A61K31/38
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