摘要 |
A process for methylating 2,2,6,6-tetramethylpiperidin-4-one with formaldehyde and formic acid in an organic solvent, comprising (A) addition of the formaldehyde to the 2,2,6,6-tetramethylpiperidin-4-one and formation of a 1-hydroxymethyl-2,2,6,6-tetramethylpiperidin-4-one intermediate and (B) subsequent addition of the formic acid to the 1-hydroxymethyl-2,2,6,6-tetramethylpiperidin-4-one intermediate and formation of 1,2,2,6,6-pentamethylpiperidin-4-one.
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