发明名称 |
Glycopeptide recovery process |
摘要 |
<p>A process for recovering vancomycin-type glycopeptide antibiotics which comprises 1) commingling the fermentation medium in which the antibiotic is produced with a polystyrene divinylbenzene resin such as Dow XFS-43278.00, 2) separating the resin from the medium and 3) eluting the antibiotic from the resin. This improvement avoids preliminary filtration and pH adjustment of the broth, simplifies waste-disposal problems and eliminates antibiotic losses due to mycelial adsorption and filtration.</p> |
申请公布号 |
GR3019978(T3) |
申请公布日期 |
1996.08.31 |
申请号 |
GR19960401353T |
申请日期 |
1996.05.20 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
GLASS, SUZANNE LYNN EBACH;JOHNSON, CHARLES WILLIAM;SPENCER, JOHN LAWRENCE |
分类号 |
C12P21/00;C07K1/16;C07K9/00;C12P21/02;C12P21/04;C12R1/365;(IPC1-7):C07K9/00 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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