| 摘要 |
<p>A method of the fermentative production of useful substances such as amino acids with the use of a microorganism comprising culturing the microorganism in a medium and recovering the fermentation product thus accumulated in the medium, wherein the microorganism is the one to which a tolerance to the stress suppressing its growth and/or the production of the fermentation product has been imparted by introducing at least either a gene encoding a heat shock protein or a gene encoding the σ factor acting specifically on the heat shock protein gene thereinto to thereby elevate the expression level of the heat shock protein in the cells.</p> |
