| 摘要 |
A device comprising a reversible negative electrode in contact with a reservoir element containing an electrolyte which contains an active principle such as an anionic glycosaminoglycan, particularly a low molecular weight heparin, in at least partially ionised form, a positive electrode alone or in combination with a receptacle containing any electrolyte, and an electrical signal generator connectable to both electrodes. The generator is arranged to apply electrical signals between the electrodes, which signals have an average voltage such that the current density generated between the electrodes is 0.05-0.25 mA/cm<2>. The amount of active principle in the reservoir element combined with the negative electrode is 0.5-16 mg per cm<2> of the electrode and per mAh of current through 1 cm<2> of the electrode. |
