Nucleotide and peptide sequences of the USHER-lB gene diagnostic and therapeutic applications

摘要

The invention relates to DNA comprising all or part of a nucleotide sequence selected from SEQ ID N DEG 1, sequences hybridizing to all or part of SEQ ID N DEG 1 and any sequence which code for the same aminoacid sequence as encoded by the nucleotide sequence SEQ ID N DEG 1 due to the degeneracy of the genetic code, as well as to a method of selection of a genetic abnormality linked to a syndromic or non-syndromic deafness and a pharmaceutical composition comprising all or part of the nucleic acid of a gene encoding an unconventional myosin molecule.