发明名称 VENLAFAXINE IN THE TREATMENT OF HYPOTHALAMIC AMENORRHEA IN NON-DEPRESSED WOMEN
摘要 This invention provides a method for treating hypothalamic amenorrhea in a non-depressed female mammal by administering to the mammal an effective amount of a hydroxycycloalkanephenethyl amine compound of the following structural formula: in which A is a moiety of the formula wherein the dotted line represents optional unsaturation; R1 is hydrogen or alkyl; R2 is alkyl; R4 is hydrogen, alkyl, formyl, or alkanol; R5 and R6 are, independently, hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, dialkylamino, alkanamido, halo, trifluoromethyl, or taken together, methylene dioxy; R7 is hydrogen or alkyl; and n is 0, 1, 2, 3, or 4; or a pharmaceutically acceptable salt thereof.
申请公布号 CA2167999(A1) 申请公布日期 1996.07.31
申请号 CA19962167999 申请日期 1996.01.24
申请人 AMERICAN HOME PROUCTS CORPORATION 发明人 UPTON, GERTRUDE V.;DERIVAN, ALBERT T.;RUDOLPH, RICHARD L.
分类号 A61K31/135;A61K31/13;A61K31/137;A61P13/02;A61P15/00;A61P43/00;(IPC1-7):A61K31/135;A61K31/275 主分类号 A61K31/135
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