| 发明名称 |
N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives |
| 摘要 |
<p>N-(Acyl)glutamic acid derivatives in which the acyl group is substituted with 4-hydroxypyrrolo[2,3-d]pyrimidin-3-yl group are antineoplastic agents. A typical embodiment is N-[4-(2-{4-hydroxy-6-aminopyrrolo[2,3-d]pyrimidin-3-yl}-ethyl)benzoyl] -L-glutamic acid.</p> |
| 申请公布号 |
GR3019784(T3) |
申请公布日期 |
1996.07.31 |
| 申请号 |
GR19960401164T |
申请日期 |
1996.04.29 |
| 申请人 |
THE TRUSTEES OF PRINCETON UNIVERSITY;ELI LILLY AND COMPANY |
发明人 |
TAYLOR, EDWARD C.;KUHNT, DIETMAR G.;SHIH, CHUAN;GRINDEY, GERALD B. |
| 分类号 |
C07D487/04;A61K31/195;A61K31/505;A61K31/519;A61P35/00;A61P35/02;A61P43/00;(IPC1-7):C07D487/04 |
主分类号 |
C07D487/04 |
| 代理机构 |
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