Genes differentially expressed in metastatic and non-metastatic rat rhabdomyosarcoma cell lines

摘要

The present invention relates to polynucleotide sequences and proteins that are differentially expressed in invasive or metastasis cancer cells during malignant tumor progression of cancer, for example in rhabdomyosarcoma and which may thus serve as general molecular markers in metastatic disease as well as providing a basis for therapy. The present invention also relates to a method of diagnosis of malignant diseases based on the detection of such markers.