发明名称 |
Composition and methods for transdermal delivery of acid-lability drugs |
摘要 |
A transdermal penetration-enhancing, drug acid-lability reducing composition and related method are described. Specifically, the transdermal composition comprises: (a) a therapeutically effective amount of a pharmacologically active drug which is subject to acid catalyzed degradation; (b) a pharmaceutically acceptable carrier substantially free of a lower alkanol; and (c) a penetration-enhancing amount of a functional derivative of a fatty acid. Such compositions increase the usefulness of transdermal compositions that rely upon an organic acid such as oleic acid penetration enhancer. |
申请公布号 |
ZA9600070(B) |
申请公布日期 |
1996.07.18 |
申请号 |
ZA19960000070 |
申请日期 |
1996.01.05 |
申请人 |
NOVEN PHARMACEUTICALS, INC. |
发明人 |
CHENSHENG LI |
分类号 |
A61K9/70;A61K31/195;A61K31/215;A61K31/565;A61K47/10;A61K47/18 |
主分类号 |
A61K9/70 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|