Process for the preparation of halogenated beta -lactam compounds
摘要
There is described the preparation of halogenated beta -lactam derivatives by introduction of a chlorine atom in the 3-position of the cephem nucleus starting from a 3-sulfonyloxycephem. Such starting materials are reacted with a chlorine ions donor in a basic medium.
申请公布号
US5532353(A)
申请公布日期
1996.07.02
申请号
US19930058714
申请日期
1993.05.10
申请人
BIOCHIMICA OPOS SPA
发明人
DA COL, MARCO;DALL'ASTA, LEONE;RESTA, IRENE;CAINELLI, GIANFRANCO;CONTENTO, MICHELE;PANUNZIO, MAURO;UMANI RONCHI, ACHILLE