发明名称 |
HAIBURITSUDOTANPAKUSHITSUOYOBIIDENSHIOKOODOSURUJUGOIDENSHI |
摘要 |
A fused gene encoding a hybrid protein, the fused gene including a first sequence encoding a fragment of the diphtheria toxin molecule which renders the hybrid protein capable of penetrating the cytoplasmic membrane of a cell and incapable of killing the cell, fused to a second sequence encoding a portion of a polypeptide ligand effective to enable the hybrid protein to bind selectively to the cell. The invention provides for labelling of targeted cells for diagnostic purposes. |
申请公布号 |
JP2510984(B2) |
申请公布日期 |
1996.06.26 |
申请号 |
JP19850502723 |
申请日期 |
1985.06.07 |
申请人 |
SERAGEN INC |
发明人 |
MAAFUI JON AARU |
分类号 |
C07K14/52;C07H21/04;C07K1/22;C07K14/00;C07K14/16;C07K14/18;C07K14/245;C07K14/25;C07K14/28;C07K14/34;C07K14/415;C07K14/435;C07K14/54;C07K14/545;C07K14/55;C07K14/575;C07K19/00;C12N1/00;C12N9/02;C12N9/24;C12N15/00;C12N15/09;C12N15/62;C12P21/02;C12Q1/02;G01N33/50;G01N33/569;G01N33/68;(IPC1-7):C12N15/09 |
主分类号 |
C07K14/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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