发明名称 Process for preparation of (2-morpholinophenyl)guanidine or pharmaceutical suitable salts thereof
摘要 The invention applies to obtaining new chemicals, namely, obtaining (2-morpholinophenyl) guanidine or its pharmaceutically eligible salts.<IMAGE>where-NR1R2 is N-methylamino-, N,N-dimethylamino-, N-ethylamino-, N-ethyl-N-methylamino-, N-butylamino-, N-methoxyethyl-N-methylamino, N-alyl-N-methylamino-, N-ethyl-N-methoxyethyl-amino-, N,N-dialylamino-, N-methylpiperazinyl-, dimethylmorpholino-, methylpiperidino-, morpholino-, or tiomorpholino groups, andR3 designates hydrogen, fluorine, chlorine atoms, and methyl- or methoxy- groups.The mentioned chemicals possess hypoglycaemic properties, and they may be used as anti-diabetic medications. The aim of the invention is to obtain new (2-morpholinophenyl) guanidines, which would possess a new type biological effect for this chemical group.
申请公布号 LV10946(B) 申请公布日期 1996.06.20
申请号 LV19940000096 申请日期 1994.05.04
申请人 THE BOOTS COMPANY PLC 发明人 GOPALAN,BALASUBRAMANIAN
分类号 C07C277/02;C07C279/18;C07D295/02;(IPC1-7):C07C277/02 主分类号 C07C277/02
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