| 摘要 |
PCT No. PCT/EP95/04552 Sec. 371 Date Jun. 3, 1997 Sec. 102(e) Date Jun. 3, 1997 PCT Filed Nov. 20, 1995 PCT Pub. No. WO96/16049 PCT Pub. Date May 30, 1996Oxazole compounds having formula (I) wherein R1 and R3 are selected from the group consisting of hydrogen, hydroxy, C1-6alkyl, C1-6alkoxy, C1-6alkoxyC1-6alkyl, phenyl or phenyl mono- or disubstituted with C1-6alkyl, halogen, hydroxy, C1-6alkoxy, aminosulfonyl, hydroxyC1-6alkyl, C1-6alkylsulfonylaminoC1-6alkyl or carbamylC1-6alkylaminosulfonyl; R2 is selected from hydrogen, C1-6alkyl, hydroxyC1-6alkyl, C1-6alkoxy, C1-6alkoxyC1-6alkyl or (fluorinated C1-6alkyl)oxyC1-6alkyl; W is a C1-6alkylene chain or nitrogen; m is independently the integer 0 or 1; X is CH or nitrogen, provided that when W is nitrogen then X is CH; q is independently an integer selected from the group consisting of 1, 2, 3 or 4; or a pharmaceutically acceptable acid-addition or base-addition salt thereof, pharmaceutical compositions containing them and their use in therapy. |
