摘要 |
<p>An anti-HIV drug containing as the active ingredient one or more phosphodiester-linkage oligodeoxynucleotides represented by the following general formula (I): Pn(Gp)mG (I) wherein G represents a 2'-deoxyguanosine structure; p represents a phosphate residue forming an ester linkage with the adjacent G, and the terminal p forms an ester linkage with the 5'-hydroxyl group of the 5'-terminal G, while each of the p's positioned between two G's forms ester linkages with, respectively, the 3'-hydroxyl group of the lefthand G and the 5'-hydroxyl group of the righthand G in the formula; n represents a number of 0 or 1; and m represents a number of 4 to 15, provided m is a number of 6 to 15 when n is 0.</p> |