| 摘要 |
<p>A reaction system, wherein a cyanohydrin is converted into an optically active alpha -hydroxy acid or alpha -hydroxyamide via a treatment in a reaction tank (f) with a microorganism, is provided with an automatic cyanohydrin controller (h) comprising a cyano ion detector (a), a regulator (b) and a cyanohydrin supplier (i) and (j) linked thereto. The reaction is performed while automatically controlling the cyanohydrin concentration. Thus cyanohydrin can be supplied under automatic control at a relatively low and constant concentration on the basis of its consumption ratio. The reaction rate of the catalyst can be continuously regarded as the rate-limiting factor. As a result, a decrease in the enzymatic activity during the reaction can be suppressed and an optically active alpha -hydroxy acid or alpha -hydroxyamide can be efficiently obtained at a high yield.</p> |
