发明名称 |
Covalent attachment of thiazole orange to oligonucleotides for use in nucleic acid detection |
摘要 |
The present invention relates to conjugates of a cyanine dye and an oligonucleotide. When these conjugates hybridize or bind to a target, a detectable increase in fluorescence intensity or change in fluorescence polarization is observed.
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申请公布号 |
EP0710668(A2) |
申请公布日期 |
1996.05.08 |
申请号 |
EP19950304988 |
申请日期 |
1995.07.18 |
申请人 |
BECTON DICKINSON AND COMPANY |
发明人 |
LINN, C. PRESTON;PITNER, J. BRUCE;MIZE, PAT D. |
分类号 |
G01N33/50;C07H21/00;C09B23/00;C12N15/09;C12Q1/68;(IPC1-7):C07H21/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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