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发明名称
Antibody-drug conjugates
摘要
Derivatized drugs are prepared with a linker consisting of a malonate, wherein the drug is linked through a methylene to the 2-position carbon of the malonate.
申请公布号
US5514794(A)
申请公布日期
1996.05.07
申请号
US19910644366
申请日期
1991.01.22
申请人
ELI LILLY AND COMPANY
发明人
BARTON, RUSSELL L.
分类号
C07H15/252;A61K39/395;A61K47/48;A61P35/00;C07C69/734;C07C235/28;C07D519/04;C07H15/26;C07H17/04;C07K1/113;C07K14/00;C07K16/00;(IPC1-7):C07D265/30
主分类号
C07H15/252
代理机构
代理人
主权项
地址
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