发明名称 Novel alpha,alpha,alpha',alpha'-tetrachlorobicarboxylic acids, process for producing them and medicaments containing them
摘要 Compound of formula (I) in which A and A' are mutually independently a straight or branched alkylene chain with 1-10 carbon atoms, B is ortho, meta or para-phenylene, 1,2, 1,3 or 1,4-cyclohexylidene, sulphur, oxygen or NR1 in which R1 may be hydrogen, benzyl, phenyl or a C1-C4 alkyl radical, a carbonyl, sulphoxide or sulphone group, an E or Z-vinylene or an acetylene group, a CR2-R3 group, R2 is hydrogen, a C1-C4 alkyl radical or phenyl, R3 is a C1-C4 alkyl radical, benzyl, phenyl, hydroxy or a NR4R5 group, R4 is hydrogen, benzyl, phenyl or a C1-C4 alkyl radical, and R5 may be a hydrogen or a C1-C4 alkyl radical, a Y-W-Y group, Y is sulphur or oxygen and W is an alkylene chain (CH2)n, and n may be 1-15, their optical isomers and their physiologically compatible salts and esters, process for producing them and medicaments containing these compounds for the treatment of metabolic syndrome.
申请公布号 AU3840695(A) 申请公布日期 1996.05.06
申请号 AU19950038406 申请日期 1995.10.10
申请人 BOEHRINGER MANNHEIM GMBH 发明人 EDGAR VOSS;JOHANNES PILL;PETER FREUND
分类号 C07C57/58;C07C317/44;C07C323/52 主分类号 C07C57/58
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