NOVEL PHENYLETHYL AND PHENYLPROPYLAMINES

摘要

PCT No. PCT/SE94/00860 Sec. 371 Date Oct. 26, 1994 Sec. 102(e) Date Oct. 26, 1994 PCT Filed Sep. 16, 1994 PCT Pub. No. WO95/09835 PCT Pub. Date Apr. 13, 1995Compounds of the general formula or pharmaceutically acceptable salts thereof, wherein Z is a saturated or unsaturated 3 to 6 carbon chain, m is 2 or 3, R1 is a hydrogen atom, or a straight or branched C1-4 alkyl group, R2, R3 and R13 are situated in the ortho, meta, or para position of the phenyl ring and are the same or different and selected from the following groups: H, OH, OR14, halogen, CO2R9, CN, CF3, NO2, NH2, COCH3,OSO2CF3,OSO2CH3,CONR10R11, OCOR12, wherein R9, R12 and R14 is a straight or branched C1-4 alkyl group, R10 and R11 are the same or different and represents hydrogen or a straight or branched C1-6 alkyl group, R is 1) or or or wherein the variables are defined in the specification, processes for their preparation, pharmaceutical preparations containing them and the use of the compounds in the treatment psychiatric disorders.