<p>Compounds of formula (I) or (Ia): <CHEM> where R is 5-indanyl or a carboxylic acid protecting group, or an amine salt thereof, are prepared by hydrogenating an (E)-allylic ether of formula (II) or (IIa): <CHEM> in the presence of a stereoselective rhodium or ruthenium biphosphine catalyst and a protic solvent.</p>
申请公布号
DE69300826(T2)
申请公布日期
1996.04.18
申请号
DE1993600826T
申请日期
1993.09.22
申请人
PFIZER RESEARCH AND DEVELOPMENT CO., N.V./S.A., DUBLIN, IE
发明人
CHALLENGER, STEPHEN DR., C/O PFIZER CENTRAL RES, SANDWICH, KENT, CT13 9NJ, GB