| 摘要 |
Dibenzofuran derivs. of formula (I), their optical and geometric isomers and, when R1 or R9 are an acid gp. or R9 is an amine, their salts are new: R = H, halo, lower alkyl, lower acyl or OR'; A = a gp. of formula (a) - (c); R1 = H, methyl, -CH2-O-R5, -OR5, -COR6 or -S(O)tR6; R2 = H or OR5; either R3, R4 = H, lower alkyl or -(X)n-(CH2)m-R7; or R3 + R4 = oxo, thioketone, oxime, oxime, =N-O-R6, epoxy, cycloalkyl opt. substd. by halo or lower alkyl, or -O-(CH2)q-O-; q = 2 - 3; R3', R4' = H, lower alkyl or lower acyl; t = 0 - 2; R5 = H, lower alkyl or lower acyl; R6 = H, -NR"R"' or -OR8; R7 = H or -(CO)p-R9; p = 0 or 1; R8, R' = H, 1-20C alkyl, mono- or poly-hydroxyalkyl, aryl (opt. substd.), aralkyl (opt. substd.), a sugar residue or an amino acid residue; R9 = H, alkyl, alkenyl, alkynyl, aryl or -NR"R"'; or R9 is also -OR7 provided that m is not 0; R", R"' = H, lower alkyl, mono- or polyhydroxyalkyl, aryl (opt. substd.), aralkyl (opt. substd.), an amino acid, peptide, or sugar residue; or NR''R''' = a heterocyclyl; X = O or S; n = 0-1; m = 0-10.
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